Obtain validated functional antibody sequences in as fast as one month!
Contact Us
The traditional antibody discovery workflow relies on lengthy multi-platform processes including flow cytometry sorting, well-plate culture, ELISA, microscopic imaging and manual picking, resulting in high labor costs.
Based on self-developed Light Workbench and Light Operator P1 single-cell screening platform, MicroNano Dynamics bypasses cell fusion and library construction steps. Positive plasma cell screening can be finished within 1 day, and antibody sequences obtained in 1 week. This enables customers to complete the process from animal immunization to acquisition of antibody sequences for further functional validation in as short as one month.
| Protein | Positive Count | Exported Count | Successfully Amplified Count |
|---|---|---|---|
| Human uPAR | 121 | 96 | 73 |
| Cyno uPAR | 92 | ||
| Mouse uPAR | 30 |
Single B-cell screening for higher diversity of antibody sequences
By ELISA assay, antibody sequences obtained via single B-cell screening exhibit strong binding affinity to human antigen proteins.